richard edson in Ferris Bueller's Day Off

Nobody got this one:

Huey Lewis was the judge for the dance competition in Back to the Future.

It's okay, for the longest time I didn't know that either.

Anthony Kiedis in Point Break...he gets shot in the foot.

Grace Jones: A View To A Kill, Conan The Destroyer, Vamp to name a few

Henry Rollins in The Chase.
An awful movie.

The Chase... The 1994 film directed by Adam Rifkin (aka Rif Coogan)? That film is great!

Hum.
The sex scene in the car, while driving and being chased by cop cars, that was the worst.

But it had Henry Rollins playing a cop for God sakes! A man who had been singing "Police Story" ten years earlier at the time!

And Anthony Kedis and Flea as rednecks! You gotta love that.

art garfunkel in bad timing
tom waits was also in the wristcutters
george harrison in life of brian

he was playing a piece of shit cop at that. yeah rollins was the best part of that movie.

Tom Waits - Down By Law
Nick Cave - Ghosts of the Civil Dead, that Jesse James movie.
Henry Rollins - Heat, Johnny Mnemonic etc
Bowie - Merry Christmas Mr. Lawrence, Christiane F, Just a Gigolo
FM Einheit & Genesis P Orridge - Decoder
Not sure if it counts, but Blixa Bargeld was the Mummy's growl in 'The Mummy'

Lou Reed's been in a few movies as well - Prozac nation, One Trick Pony.

Jello Biafra - Terminal City Ricochet,Tapeheads,and most recently Retardead.
I've not seen any of these...

thurston moore and jad fair in the devil and daniel johnston..
and of course daniel johnston himself :P

and nirvana, sy, dinosaur, bit, etc in 1991.