Bubonic plague
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Plague ICD-10 A20. ICD-9 020 DiseasesDB 14226
Yersinia pestis seen at 2000x magnification. This bacterium, carried and spread by fleas, is the cause of the various forms of the disease plague.
Bubonic plague is the best-known variant of the deadly
infectious disease plague, which is caused by the
enterobacteria Yersinia pestis.
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Overview
Plague has affected human society for millennia. A lot of scientists believe that it was responsible for the
Black Death, which killed perhaps a third of Europe's population during the Middle Ages, with additional large numbers of casualties in Asia and the Middle East.
Plague is
endemic in many countries in Africa, in the former Soviet Union, the Americas and Asia. In 2003, nine countries reported 2,118 cases to the
WHO (World Health Organization), of which 182 ended in death. All were isolated cases, except for an outbreak in a village in Algeria (the first in fifty years), which caused eleven infections and one death. Plague is most common in
Madagascar and the
Democratic Republic of the Congo. These two countries have on average 600 to 800 cases each year. They accounted for 2,025 of the 2,118 cases and 177 of the 182 deaths in 2003. Other countries with annual but many fewer cases are
Tanzania,
Peru,
United States,
China,
Mongolia and
Vietnam. According to the WHO, the actual number of cases in the world is probably much higher than reported, due to the reluctance of certain countries to declare cases, the lack of diagnosis because the clinical picture of cases is not very specific, and the absence of laboratory confirmation
The most recent outbreak of plague happened in Zobia, in the northern part of the
Democratic Republic of the Congo in December 2004. The outbreak, which only appeared as the variant pneumonic plague, began among workers in a diamond mine. By mid-March 2005, when the
WHO regarded the outbreak as over, 130 people had been infected, of whom 97 died.
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There has not been a plague
epidemic (i.e an outbreak affecting a larger area) for many years.
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