Yeah, but the Simpsons aren't just a "pop-culture-reference humorfest", they actually DO have real jokes. Like, I think pop culture referencing makes up perhaps.. 20% of the show. The Simpsons are timeless.
The other two shows you mentioned, though, wow.. yeah.. they could barely exist on their own merits, because they base whole episodes around making fun of other things in pop culture. South Park is by far one of the worst fucking shows I've ever seen, just terrible, I've seen about 50+ episodes of it and haven't laughed once (can't believe South Park is left to be on season infinity but a good fucking show like Futurama or Super Milk Chan is shunned!). Family Guy is pretty hit-or-miss as a television show, but indeed it's random flashbacks to pop culture pretty much make up 75% of the humor -- though, they DO riff on a lot of obscure pop culture moments that might go over some younger viewer's heads (like commercials from the 80's). So yeah.
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