I use Audition at the radio station for making promos, PSAs and Calendars, but I don't think I'd like it much for doing actual music. I don't like the way the effects work particularly, though their o.k. if you just want to put echo on your voice or something simple.
Mostly I use Garage Band now, but I've been perfectly happy with Audacity at times before I got it. I liked Sound Forge a lot too, but it's PC only, which is weird since it's such a Macish interface and style. I've used a few others too, but nothing that jumps to mind as super good. Given a decent sound quality (and they usually are all pretty close to the same) easy to use it's what's important to me.
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